Genuine Postinor 1 Tablet Plan B Emergency Contraceptive Levonorgestel - Free Ship
POSTINOR prevents a pregnancy before it is established by preventing or delaying the release of an egg from the ovary (by preventing ovulation) with the help of a hormone called Levonorgestrel, the same hormone found in many regular contraceptives. It doesn’t work if you are already pregnant and will not harm an already established pregnancy. The sooner you take POSTINOR, the more effective it is.
POSTINOR is a single Emergency Contraceptive Pill (ECP) which safely prevents unwanted accidental pregnancy within 72 hours after unprotected sexual intercourse.
Why is POSTINOR unique?
POSTINOR is effective to prevent pregnancy when taken as directed up to 72 hours (3 days) after unprotected sex. If you take POSTINOR it is 99% sure that you avoid pregnancy
Producer of ESCAPELLE manufactures Levonorgestrel emergency contraceptive pills under the brand name POSTINOR and ESCAPELLE for more than 35 years. POSTINOR were used in more than 400 million cases without any serious adverse event.
Producterr has become No. 1 Emergency Contraception manufacturer reaching more than 100 countries with highest quality Emergency contraceptive pills worldwide.
Each tablet contains 1,50 mg of levonorgestrel.
A. 21.8.2 Progesterones with or without oestrogens
The precise mode of action of levonorgestrel is not known. Emergency hormonal contraception is thought to work mainly by preventing fertilisation by altering tubal transport of sperm and/or ova. It may also cause endometrial changes that discourage implantation.
Efficacy: It has been estimated that levonorgestrel prevents 84% of expected pregnancies. At the recommended regimen, levonorgestrel is not expected to induce significant modification of blood clotting factors, and lipid and carbohydrate metabolism.
Orally administered levonorgestrel is rapidly and almost completely absorbed.
The results of a pharmacokinetic study carried out with 16 healthy women showed that following ingestion of one tablet of levonorgestrel, maximum drug serum level of 18,5 ng/mL was found at 2 hours. The mean value of area under the levonorgestrel concentration-time curve (0-infinity) was calculated as 310,2 ng.h/mL. After reaching maximum serum levels, concentration of levonorgestrel decreased with mean elimination half-life of about 26 hours.
Levonorgestrel is not excreted in unchanged form but as metabolites. Levonorgestrel metabolites are excreted in about equal proportions with urine and faeces. The biotransformation follows the known pathways of steroid metabolism; the levonorgestrel is hydroxylated in the liver and the metabolites are excreted as glucuronide conjugates. No pharmacologically active metabolites are known.
Levonorgestrel is bound to serum albumin and sex hormone binding globulin (SHBG). Only about 1,5% of the total serum levels are presented as free steroid, but 65% are specifically bound to SHBG.
Following ingestion of one tablet of levonorgestrel the mean value of SHBG was about 40 nmol/L. Serum levels of SHBG tend to stay at these levels (or slightly increased) up to 24 hours, and then gradually decrease to reach levels of approximately 30 nmol/L at 192 hours.
The absolute bioavailability of levonorgestrel was determined to be almost 100% of the dose administered.
Emergency contraception within 72 hours of unprotected sexual intercourse or failure of a contraceptive method.
Hypersensitivity to the active substance levonorgestrel or to any of the excipients.
Severe hepatic insufficiency.
Pregnancy or suspected pregnancy (see Pregnancy and Lactation).
Emergency contraception is an occasional method to be used in an “emergency situation” only. It should in no instance replace a regular contraceptive method. POSTINOR does not prevent a pregnancy in every instance. If there is uncertainty about the timing of the unprotected intercourse or if the woman has had
Emergency contraception is an occasional method to be used in an "emergency situation" only. It should in no instance replace a regular contraceptive method. POSTINOR does not prevent a pregnancy in every instance.
If there is uncertainty about the timing of the unprotected intercourse or if the woman has had unprotected intercourse more than 72 hours earlier in the same menstrual cycle, conception may have occurred. Treatment with POSTINOR following the second act of intercourse may therefore be ineffective in preventing pregnancy. If menstrual periods are delayed by more than 5 days or abnormal bleeding occurs at the expected date of menstrual periods or pregnancy is suspected for any other reason, pregnancy should be investigated.
If pregnancy occurs with treatment with POSTINOR, the possibility of an ectopic pregnancy should be considered, especially in those women who present with abdominal/pelvic pain or collapse and those with a history of ectopic pregnancy, fallopian tube surgery or pelvic inflammatory disease.
The metabolism of POSTINOR is enhanced by concomitant use of liver enzyme inducers. Medicines suspected of having the capacity to reduce the efficacy of levonorgestrel containing medication include barbiturates (including primidone), phenytoin, carbamazepine, herbal medicines containing Hypericum perforatum (St. John's Wort), rifampicin, ritonavir, rifabutin, griseofulvin, ampicillin and other antibiotics, including medicines used to treat tuberculosis, cyclosporine (see below).
The requirement for oral antidiabetics and insulin can change as a result of an effect on glucose tolerance.
Medicines containing levonorgestrel as in POSTINOR may increase the risk of cyclosporine toxicity due to possible inhibition of cyclosporine metabolism.
PREGNANCY AND LACTATION
POSTINOR should not be given to pregnant women and will not interrupt the pregnancy. In case of failure of this emergency contraception with developing pregnancy, epidemiological studies indicate no adverse effects of progestogens.
- 4 years from manufacture date.
- Geodeon Richte PLC - Hungary
- 1 Box 1 Capsules
- Store at dry, cool place (under 30oC).
- Protect from direct sunlight.
- Keep out of reach of children.
|Formulation||Pill/ Tablet/ Capsule|
|Package||Box (1 blister x 1 tablets)|
|Country of Manufacture||Hungary|